![]() It can also cause medical problems with your heart, lungs, nerves, eyes and skin.ĭoctors don't know what starts this process, although a genetic component appears likely. In rheumatoid arthritis, your immune system attacks healthy tissue in your joints. Normally, your immune system helps protect your body from infection and disease. Rheumatoid arthritis is an autoimmune disease. Request an Appointment at Mayo Clinic Causes Make an appointment with your doctor if you have persistent discomfort and swelling in your joints. ![]() Over time, rheumatoid arthritis can cause joints to deform and shift out of place. Periods of increased disease activity, called flares, alternate with periods of relative remission - when the swelling and pain fade or disappear. Rheumatoid arthritis signs and symptoms may vary in severity and may even come and go. In most cases, symptoms occur in the same joints on both sides of your body.Ībout 40% of people who have rheumatoid arthritis also experience signs and symptoms that don't involve the joints. Joint stiffness that is usually worse in the mornings and after inactivityĮarly rheumatoid arthritis tends to affect your smaller joints first - particularly the joints that attach your fingers to your hands and your toes to your feet.Īs the disease progresses, symptoms often spread to the wrists, knees, ankles, elbows, hips and shoulders. ![]() Signs and symptoms of rheumatoid arthritis may include: ![]()
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